Educational materials for dental professionals: product video, downloadable case studies, and peer-reviewed publications on Ubigel Inperio and its active principles.
USER GUIDE & CASE STUDIES
The clinical situation of patients who have benefited from treatment with Ubigel Inperio visibly improves after just one application. Patients interviewed one week after the first application reported an improvement in gum conditions, with less bleeding, less pain when brushing, and less redness.
Conservative management of inflammatory epulis: combined treatment with photodynamic therapy and periodontal gel. Inflammatory epulis is a benign reactive lesion that affects the gingival tissue, often linked to chronic irritative factors, including plaque and tartar. It affects young women more frequently, especially during pregnancy, as its onset is also linked to hormonal factors.
SPERMIDINE
Spermidine is a natural low molecular weight polyamine widely distributed in various organisms.
It has a high capacity to promote the reparative effect of periodontal, bone and dental tissue damaged by the erosive effects of periodontitis. Its structure is crucial for functions that include DNA stabilization, promotion of cell growth, and induction of autophagy.
PUBLISHED RESEARCH
Peer-reviewed studies on hyaluronic acid, spermidine, and clinical outcomes relevant to Ubigel Inperio. Download the full PDF for each article.
Cells 2025, 14, 1047
Dolaji Henin, Elena Canciani, Daniela Carmagnola, Stefano Ferrero, Gaia Pellegrini, Mariachiara Perrotta, Riccardo Sirello, Claudia Dellavia, Nicoletta Gagliano
Research on the synergistic effect of spermidine and hyaluronic acid in oral regenerative applications.
Clinical Oral Investigations (2024) 28:537
Vincenzo Iorio-Siciliano, Dario Marasca, Leopoldo Mauriello, Enzo Vaia, Stefan-Ioan Stratul, Luca Ramaglia
Clinical trial evaluating local adjunctive delivery in peri-implant mucositis management.
CPQ Dentistry (2019) 1:4
Daniela Carmagnola, Carlo Angelo Ghisalberti, Gaia Pellegrini, Lucrezia Cinquanta, Marilisa Toma, Claudia Dellavia
Ubigel supports connective tissue activity by stimulating protein exchange and production that promote cellular activities for periodontal well-being, without altering morphology, and supports gingival healing in periodontitis as an adjunct to professional care.
Educational PDFs and video are provided for qualified dental professionals. For full indications, contraindications, and instructions for use, refer to official product labeling and manufacturer materials.
